Single-use Bioprocessing Market

Global Single-use Bioprocessing Market Size (2024 to 2032)

The global single-use bioprocessing market is estimated to be worth USD 19.64 billion by 2032 and USD 5.4 billion in 2024, growing at a CAGR of 17.5% from 2024 to 2032.

Current Scenario of the Global Single-use Bioprocessing Market

Single-use bioprocessing is majorly utilized in the manufacturing of biopharmaceuticals. The technique is used throughout biopharmaceutical production, from buffer and media preparation to biologics shipping. Single-use bioprocessing techniques are carried out through different products. Some leading products include manifold assemblies, bioprocess containers and bags, single-use bioreactors, and single-use mixers. These items lower the expenditure associated with the complex bioproduction procedures, such as cleaning, sterilization, and care of the big bioreactors. Single-use bioprocessing technology utilizes single-use products that are extensively used in producing vaccines and therapeutics. The global single-use bioprocessing market has witnessed substantial growth in the past few years and is predicted to have notable growth during the forecast period. These single-use products comprise various types of plastic material, mainly polyamide. Single-use systems are widely used in biopharmaceutical manufacturing due to their various benefits compared to traditional reusable equipment practices.

MARKET DRIVERS

The growing demand for biopharmaceuticals and increasing R&D activities by pharmaceutical companies propel the global single-use bioprocessing market growth.

According to BioPharm International, around 85% of the pre-commercial biomanufacturing includes single-use bioprocessing infrastructure. With the rising demand for pharmaceutical products worldwide, a wide range of advanced technologies comprises automation, big data, and machine learning. In addition, the rising importance of reproduced single-use products, the establishment of ongoing biomanufacturing, and healthcare industry enhancements are other factors fuelling the global single-use bioprocessing market.

In addition, the growing popularity of disposables in biopharmaceutical manufacturing, the rising incidence of chronic diseases leading to the need for biological treatment, affordable disposable products and instruments, and the developing life science research infrastructure drive the global single-use growth bioprocessing systems market. Moreover, advancements in the technology of bioprocessing systems also fuelled the global single-use bioprocessing systems market. Therefore, growing numbers of joint ventures, acquisitions, and quick launches of new products are the significant trends in this global single-use bioprocessing systems market. The escalation in the advancements of the healthcare industry and the rising adoption of advanced technologies for manufacturing and production of consumables are fueling the market growth. The rising awareness regarding the benefits of single-use systems as they restrict contamination due to single-use and disposal, which is crucial in the pharmaceutical and biotechnology firms, is increasing the market revenue.

The expanding market in emerging nations, owing to their wide adoption of advanced technologies and the enlarging healthcare systems, is creating market growth opportunities. Most organizations know the advantages of single-use systems over traditional stainless steel systems. This reduces the risk of contamination, lowers costs, and facilitates easy disposal, augmenting market growth in the coming years. The favorable government initiatives in countries such as China, India, and Brazil are estimated to offer substantial growth to the market.

MARKET RESTRAINTS

The extractability problems with disposing of plastic bags and possible environmental harm are the factors restricting the growth of the single-use bioprocessing market.

Moreover, the waste disposal of single-use processes is also a significant market challenge. Therns related to the quality and consistency of the products and high costs associated with the single-use products, along with the risk of breakage and damaged products, which may lead to contamination, are a few factors limiting the market expansion. The presence of limited downstream solutions and the limitations in the mammalian cell culture due to low oxygen levels in the bioreactors are other primary factors hindering the global market growth rate. The increased concerns regarding disposal, expensive rates of consumables, and complications in storage are estimated to restrain the market growth due to limited adoption rates. The limited awareness among healthcare providers and restricted budgets for smaller and middle-income organizations will limit the market revenue expansion.

The presence of stringent regulations regarding the approval of the products owing to the quality, safety, and efficacy standards leads to complexity. It increases the overall price of the product, leading to significant challenges to market expansion. The need for interoperability due to no standardization in the industry and the growing environmental concerns regarding the disposal of the products impedes market growth.  

REPORT COVERAGE

SEGMENTAL ANALYSIS

Global Single-use Bioprocessing Market Analysis By Product

The media bags and containers segment dominated the single-use bioprocessing market with a prominent share, and it is estimated that it will maintain domination during the forecast period. Single-use bags and containers limit the usage of traditional glass and plastic products in bioprocess applications, boosting the adoption of single-use bags and leading to segment growth. Single-use bags and containers provide various benefits, which save time in cleaning and sterilization processes and limit the risk of contamination; these factors propel the global market growth.

The single-use bioreactors segment is expected to record considerable growth during the forecast period. The disposable bioreactors have disposable bags instead of culture vessels, which allows the processors to avoid the risk of contamination; this factor enhances the adoption of disposable technology, leading to the segment growth rate.

Global Single-use Bioprocessing Market Analysis By Application

Due to the increased demand for single-use filtration systems, the filtration segment held the most prominent share in the single-use bioprocessing market. The single-use systems involve membrane filters, depth filters, flow filters, and other filtration assemblies. Most of the significant market players are investing in membrane filtration assembly to enhance downstream bioprocessing, which boosts the global market growth rate. The increasing demand for efficient filtration, especially in pharmaceuticals and biotechnology, is to avoid contaminants and make the product pure and clean. The demand for single-use filtration systems is contributing to the market growth.

The storage segment is projected to have notable growth during the forecast period owing to the increased utilization of disposable bags and containers across the organizations. These are widely used to safely handle pharmaceutical liquids in most bioprocessing applications, accelerating the segment growth rate. The CellStor single-use bags are extensively used in bioprocessing in various stages such as buffer preparation, harvesting of solid-liquid separation, and others.

REGIONAL ANALYSIS

Geographically, the North American single-use bioprocessing market is predicted to lead the global market, followed by Europe during the forecast period. The growing adoption of biopharmaceutical manufacturing services and rising investments in R&D propel the regional market. The U.S. led the North American market in 2023, expected to continue throughout the forecast period. The increased expenditure on healthcare and biologics spurs U.S. market growth. Furthermore, the continuous product launches and growing popularity of disposables are expected to favor the U.S. market. The Canadian market is expected to hold a substantial share of the North American market during the forecast period owing to the low production costs, growing awareness, and increasing incidence of chronic diseases.

The European single-use bioprocessing market accounted for a substantial share of the global market in 2023. Factors such as increasing R&D activities, growing disposable biopharmaceuticals, and immense manufacturing capabilities expand the market growth. The U.K. single-use bioprocessing market is presently leading the EU market and is forecasted to continue to play a leading role during the forecast period. On the other hand, the German market is predicted to have a tremendous growth rate due to a surge in biopharmaceutical and biotech companies, intensifying system sales. According to Statista data, the number of committed biotech companies in Germany was 593 in 2015 and has risen to 679 in 2018.

However, the single-use bioprocessing market in APAC will grow at the highest CAGR because of ample investment opportunities, especially in China, India, Australia, and New Zealand. Growing government initiatives and the efforts of key market participants to better the healthcare infrastructure is favoring the market. The Chinese market is well-known for exporting biopharmaceutical activities such as chemical drugs. In July 2019, Sartorius opened a tech support center for biotech processing in Zhangjiang, Shanghai, China. The Indian single-use bioprocessing market has had a reasonable growth rate throughout the forecast period. The rising patient count, novel diseases, and accentuating lifestyle changes are supporting the Indian market.

The single-use bioprocessing market in Latin America is predicted to have a substantial growth rate during the forecast period. The local manufacturers' focus on expanding their product portfolio, and launching new advanced technology products, are driving the Latin American market. As a result, Brazil is expected to lead the Latin American market.

The single-use bioprocessing market in MEA is projected to witness a sluggish growth rate during the forecast period. Growing demand for cost-effective bioprocessing systems is expected to drive the market.

KEY MARKET PARTICIPANTS

Some of the prominent companies leading single-use bioprocessing market profiled in this report are Thermo Fisher Scientific, Danaher Corporation, GE Healthcare (General Electric Company), Sartorius Stedim Biotech S.A, Merck Millipore (Merck Group), 3M Company, Eppendorf AG, Finesse Solutions, Inc., Applikon Biotechnology B.V., and Cesco Bioengineering Co., Ltd.

RECENT MARKET DEVELOPMENTS

• In January 2024, CDMO announced its plan to expand its pharmaceutical manufacturing capacities across the Asian region. This initiative supports the worldwide demand for biologics and advanced medical products, which is expected to enhance the company's industry profile.
• In April 2024, Cytiva announced the launch of the Xcellerex magnetic m, a single-use system with 2000 and 3000 L capacities. This is used in the large-scale production of monoclonal antibodies, vaccines, and genomic medicine processes.
• In September 2023, Getinge announced the launch of its new single-use bioreactor, AppliFlex ST GMP. It is available in various sizes and provides a sustainable manufacturing solution for mRNA production and cell gene therapies.
• In April 2023, Merck introduced Ultimus, a single-use process container film. This is estimated to provide superior strength and leak resistance to the single-use assemblies.

DETAILED SEGMENTATION OF THE GLOBAL SINGLE-USE BIOPROCESSING MARKET INCLUDED IN THIS REPORT

This research report has segmented and sub-segmented the global single-use bioprocessing market based on product, application and region.

By Product

• Media Bags and Containers
• Filtration assemblies
• Single-use Bioreactors
• Disposable Mixers
• Others

By Application

• Filtration
• Storage
• Cell Culture
• Mixing and Purification

By Region

• North America
• Europe
• Asia Pacific
• Latin America
• The Middle East and Africa