Nucleic Acid Isolation And Purification Market

Global Nucleic Acid Isolation and Purification Market Size (2024 to 2029)

The size of the global nucleic acid isolation and purification market was valued at USD 4.13 billion in 2024 and is expected to grow at a CAGR of 8.27%, to reach USD 6.14 billion by 2029. 

NAIP is a procedure of purifying DNA from the collected sample using physical and chemical processes.

MARKET DRIVERS

The growing demand for genetic testing and personalized medicine primarily drives the nucleic acid isolation and purification market growth.

The usage of nucleic acid isolation and purification products in genetic testing and personalized medicine has increased dramatically in the recent past and the trend is likely to continue in the coming years and favor the market. People around the world have gained an understanding of the potential benefits of genetic testing such as the identification of genetic variations that may cause diseases or affect drug response. The nucleic acid isolation and purification products are used to extract the DNA or RNA of a patient in the process of genetic testing. The growing demand for genetic testing is likely to fuel the need for nucleic acid isolation and purification products and contribute to market growth. On the other hand, the preference for personalized medicine from the patient population of various diseases has increased notably in recent years. Nucleic acid isolation and purification also play a vital role in the development process of personalized medicine and the rising demand for personalized medicine is likely to boost the market growth.

The growing number of R&D activities in genomics and proteomics further fuels the growth rate of the nucleic acid isolation and purification market. The isolation and purification of nucleic acids such as DNA, RNA, and proteins for analysis and research purposes in genomics and proteomics fields are required. Genomics and proteomics fields have experienced several technological advancements in recent years and have seen advanced technologies and techniques that require high-quality samples to offer accurate results. Because of this, the demand for efficient and reliable nucleic acid isolation and purification methods has increased as these play a vital role in successful research in these fields.

Technological advancements contribute notably to the market’s growth rate. The rising demand for biotechnology and life sciences products, growing demand for molecular diagnostics, increasing prevalence of chronic diseases such as cancer, diabetes, and cardiovascular diseases, and increased demand for high-quality RNA isolation and purification products boost the market growth. The rising interest in gene editing and gene therapy, the increasing number of advancements in automated technologies, the rising popularity of NGS technologies, the increasing demand for CRISPR-based research, the rising need for high-throughput screening, rapid adoption of point-of-care diagnostic tests, increasing adoption of nucleic acid-based methods to detect foodborne pathogens and verify the authenticity of food products and growing demand for animal genetic testing further promote the growth of the nucleic acid isolation and purification market.

MARKET RESTRAINTS

The high cost of nucleic acid isolation and purification kits and instruments is one of the significant impediments to market growth. The complexity and time-consuming process nature of nucleic acid isolation and purification and the scarcity of skilled professionals further hinder the market growth. The stringent regulatory environment for nucleic acid isolation and purification techniques, limitations in sample quality and quantity, lack of standardization, and ethical concerns about the nucleic acid isolation and purification process inhibits the growth rate of the market.

REPORT COVERAGE

SEGMENTAL ANALYSIS

Global Nucleic Acid Isolation and Purification Market Analysis By Product

Based on the product, the kits segment held the major share of the global market in 2023 and the segmental domination is estimated to continue during the forecast period. The cost-effectiveness of kits and ease of use of these kits in applications like gene sequencing, gene cloning and molecular diagnostics majorly drive the segmental growth. These kits are used to segregate DNA or RNA from bacteria, plasmids, viruses and many more.The instruments segment is predicted to register the fastest CAGR during the forecast period. The ongoing upgrading of advanced technologically and reliable robotic systems based on various technologies like magnetic beads and spin columns propel the segmental growth.

Global Nucleic Acid Isolation and Purification Market Analysis By Technology

Based on the technology, the column-based segment captured the largest share of the global nucleic acid isolation and purification market in 2023 and the segmental domination is likely to continue during the forecast period as this column-based is so cost-effective, simple, easy, and quick. This is most commonly used in diagnostic laboratories as it requires no dangerous chemicals.

Global Nucleic Acid Isolation and Purification Market Analysis By Application

Based on the application, the DNA isolation and purification segment led the global nucleic acid isolation and purification market in 2023 and is predicted to grow at a healthy CAGR during the forecast period.

Global Nucleic Acid Isolation and Purification Market Analysis By End-User

Based on the end-user, the hospitals and diagnostic centers segment is expected to lead the nucleic acid isolation and purification market during the forecast period due to an increase in the utilization of nucleic acid-based therapeutics for early and correct diagnosis of genetic and inherited diseases. The rising number of genetic fingerprinting, prenatal testing, and liquid biopsies propel the growth of this segment.

REGIONAL ANALYSIS

The North American NAIP market dominated the market in 2023 and the same trend is anticipated to continue throughout the forecast period. The growing number of R&D activities in genomics and proteomics, the presence of leading market players in North America, and the growing demand for personalized medicine majorly propel the North American market growth. The growing patient population with chronic diseases and the rising adoption of molecular diagnostics contribute to regional market growth. Factors such as the growing number of initiatives for precision medicine and gene therapy, increasing investments by governmental organizations in R&D and funding for research activities, advancements in technology, and increasing adoption of automation further fuel the growth rate of the North American market. The U.S. held the largest share of the North American market in 2022. The domination of the U.S. market in the North American region is estimated to continue in the coming years due to factors such as increasing use of molecular diagnostics and rising emphasis on personalized medicine.

The Europe NAIP market is another promising regional market for NAIP worldwide and is predicted to hold a substantial share of the global market during the forecast period. The growing patient population of infectious diseases, increasing demand for molecular diagnostics, and the presence of well-established healthcare infrastructure in Europe majorly drive the European market. The growing geriatric population and increasing focus on precision medicine in Europe further contribute to the growth rate of the European market. The rising adoption of next-generation sequencing techniques, increasing number of initiatives from the European governments to promote personalized medicine, growing investments in R&D, rising adoption of advanced technologies, and automation in nucleic acid isolation and purification further boost the growth rate of the European market. The UK and Germany accounted for the leading share of the European market in 2023and the domination of these countries in the European market is estimated to continue throughout the forecast period.

The APAC NAIP market is predicted to register the fastest CAGR during the forecast period. The growing number of initiatives from the governments of APAC countries for the development of the healthcare sector, increasing investments in life science research, and the rising demand for personalized medicine majorly propel the APAC market growth. The growing awareness and adoption of precision medicine and genomics research in countries like China and India, the development of advanced sequencing technologies, increasing demand for DNA sequencing services, growing investments in life sciences research and development, and the presence of a large population base further fuel the growth rate of the APAC market. China and Japan occupied the leading share of the APAC market in 2022.

The Latin America NAIP market accounted for a considerable share of the global market in 2023and is predicted to grow at a healthy CAGR during the forecast period. The growing prevalence of infectious diseases, such as Zika and dengue, the increasing number of research activities and funding for genomics research in Brazil, the rising emphasis on precision medicine, and the development of companion diagnostics boost the growth of the Latin American market. Brazil followed by Mexico led the market in Latin America in 2022.

The MEA NAIP market occupied a moderate share of the worldwide market in 2022. However, the MEA market is estimated to grow at a steady CAGR during the forecast period due to the growing adoption of point-of-care testing and rapid diagnostic methods for infectious diseases, the development of advanced sequencing technologies and the rising demand for DNA sequencing services in countries like Saudi Arabia and UAE.

KEY PLAYERS IN THE GLOBAL NUCLEIC ACID ISOLATION AND PURIFICATION MARKET

Key Players Operating the Global Nucleic Acid Isolation and Purification Market Profiled in the Report are Qiagen, Bio-Rad Laboratories Inc, Illumina Inc, Agilent Technologies Inc, Thermo Fischer Scientific Inc, F. Hoffmann-La Roche AG, Sigma-Aldrich Co. LLC, General Electric Company, Danaher Corporation, Promega Corporation, Life Technologies, Roche Applied Sciences, Takara Bio, Inc.

RECENT HAPPENINGS IN THE MARKET

• In April 2020, Qiagen and Gilson made a strategic partnership that offers the researchers the capability to restrict the operator-dependent variation in manual nucleic acid extraction which results in advancing the trackability of the workflows. This collaboration of the two companies creates consistency and increases their confidence in extracting their protocols.
• In April 2020, Thermo Fisher Scientific and Hamilton both together have introduced forensic laboratories and forensic scientists have accessibility for their new business which is easy to use of automated DNA sample which is designed to extract nucleic acids.
• In July 2020, Promega Corporation Maxwell RSC 48 instrument and RSC Viral Total Nucleic acid purification kit are now sanctioned RNA extraction options in CDC diagnostic protocol for emergency use.

DETAILED SEGMENTATION OF GLOBAL NUCLEIC ACID ISOLATION AND PURIFICATION MARKET INCLUDED IN THIS REPORT

This research report on the global nucleic acid isolation and purification market has been segmented and sub-segmented into the following categories.

By Product

• Reagents
• Kits
• Instruments

By Technology

• Column-based
• Reagent-based
• Magnetic bead-based
• Others

By Application

• Genomic DNA isolation and purification
• Micro RNA isolation and purification
• Blood RNA isolation and purification
• mRNA isolation and purification
• Plasmid DNA isolation and purification
• Total RNA isolation and purification
• PCR clean up

By End-User

• Pharmaceutical and biotechnology companies
• Academic and government research institutes
• Contract research organizations
• Hospitals
• Diagnostic Centers

By Region

• North America
• Europe
• APAC
• Latin America
• Middle East and Africa