North America CAR T cell Therapy Market Research Report - By Target Antigen, Products, Application and Country (The United States, Canada and Rest of North America) – Industry Analysis on Size, Share, Trends, COVID-19 Impact and Growth Forecast (2024 to 2029)

Updated On: June, 2024
ID: 9966
Pages: 100

North America CAR T Cell Therapy Market Size (2024 to 2029)

The North American CAR T cell therapy market is expected to reach USD 1.43 billion by 2029 from USD 0.78 billion in 2024, growing at a compound annual growth rate (CAGR) of 12.88 % during the forecast period.

The North American CAR T Cell Therapy market is experiencing remarkable growth, driven primarily by the increasing incidence of various cancers, including lymphoma and leukemia.

This rising cancer burden has created a substantial patient population seeking innovative treatment options. CAR T Cell Therapy, a groundbreaking immunotherapy approach, stands out as a promising solution, particularly for patients with limited alternatives due to aggressive or refractory cancers. The therapeutic landscape has been enriched by FDA approvals and ongoing research, resulting in a greater number of CAR T cell therapy options for patients. Moreover, collaborations, improved manufacturing processes, and enhanced reimbursement policies have made CAR T cell therapy more accessible and affordable. These factors are propelling the North American CAR T Cell Therapy market, offering hope to those in need of advanced cancer treatments and underscoring its role as a pivotal player in the ongoing battle against cancer.

The market is experiencing growth, driven by its ability to address a significant unmet medical need. Many patients grappling with aggressive or refractory cancers find traditional treatments, such as chemotherapy and radiation therapy, to be ineffective, leaving them with limited therapeutic options. CAR T cell therapy emerges as a beacon of hope for these individuals. This groundbreaking immunotherapy approach involves modifying a patient's T cells to specifically target and destroy cancer cells, offering a unique and promising solution. As these therapies continue to gain FDA approvals, demonstrate their effectiveness, and expand their indications, they provide new possibilities for patients who were previously left with minimal treatment choices. The increasing recognition of CAR T cell therapy as a vital tool for managing challenging cases of cancer has significantly propelled the North American CAR T cell therapy market, offering newfound hope and optimism to those in dire need of advanced and effective treatments.

The high cost of these procedures is a significant restraint in the North American CAR T cell therapy market.

As CAR T cell therapy offers immense promise in the fight against cancer, its expense remains a substantial restraint. The costs encompass not only the intricate manufacturing process but also administration and the essential hospitalization period. The prohibitive nature of these costs poses a serious threat to patient access. Many individuals who could potentially benefit from CAR T cell therapy find it financially out of reach, thus limiting its availability and impact. Moreover, the strain on healthcare budgets is undeniable, affecting both private insurers and public healthcare systems. As the demand for this groundbreaking therapy rises, addressing the cost barrier is crucial for ensuring equitable access to CAR T cell therapy and realizing its full potential in the North American market.

Impact of COVID-19 on the North American CAR T Cell Therapy Market

The COVID-19 pandemic has had both negative and positive impacts on the North American CAR T cell therapy market. The pandemic disrupted clinical trials, delayed regulatory approvals, and diverted resources away from CAR T cell therapy research and development. The healthcare system's focus on addressing the pandemic led to reduced patient access to non-COVID-related treatments, including CAR T cell therapy. Additionally, travel restrictions and safety concerns hampered the collection and transportation of patient cells, which are essential for CAR T cell therapy production. These challenges resulted in a temporary slowdown in market growth. But, on the positive side, the pandemic accelerated the adoption of telehealth and remote monitoring, which could enhance post-treatment care and monitoring for CAR T cell therapy patients. The increased focus on vaccine development and research during the pandemic may also contribute to advances in cell therapy technologies. As the healthcare system adapts to new norms, the North American CAR T cell therapy market is expected to recover and potentially benefit from the lessons learned during the pandemic.

This research report on the North American CAR T cell therapy market has been segmented and sub-segmented into the following categories.

North America CAR T Cell Therapy Market - By Target Antigen

  • CD20
  • EGFRV III
  • CD19
  • HER2
  • MESO
  • CD22
  • BCMA
  • GD2
  • CD30
  • HER1
  • CD33

North America CAR T Cell Therapy Market - By Application

  • Multiple Myeloma
  • Chronic Lymphocytic Leukemia
  • Mantle Cell Lymphoma
  • Follicular Lymphoma
  • Diffuse large B-cell lymphoma
  • Acute Lymphoblastic Leukemia

North America CAR T Cell Therapy Market - By Product

  • Allogeneic
  • Autologous

North America CAR T Cell Therapy Market - By Therapies

  • Axicabtagene ciloleucel (Yescarta)
  • Tisagenlecleucel (Kymriah)

North America CAR T Cell Therapy Market - By End User

  • Cancer Research Centers
  • Hospitals
  • Academic and Research Institutes
  • Pharmaceutical Companies
  • Biotechnology Companies
  • Contract Research Organizations

North America CAR T Cell Therapy Market - By Country 

  • The United States
  • Canada
  • Rest of North America

North America has historically been dominant in the CAR T cell therapy market due to a large patient population, advanced healthcare infrastructure, substantial investments in research and development, and a streamlined regulatory approval process. The presence of numerous pharmaceutical and biotechnology companies engaged in CAR T cell therapy research and manufacturing has propelled North American market growth.

United States holds the largest share in the North American CAR T cell therapy market as it boasts a robust ecosystem for the research, development, and commercialization of CAR T cell therapies.

The US market also benefits from a large patient population, a well-established regulatory framework, and significant investments in research and development. Numerous CAR T cell therapies have received FDA approvals for various indications, fuelling market expansion. The US has also been at the forefront of clinical trials, providing a solid foundation for the advancement of CAR T cell therapies.

Canada has also played a significant factor in adopting and developing these therapies. The country's healthcare system is known for its universal coverage, which enhances patient accessibility to CAR T cell therapy. Collaborative efforts with international organizations and research institutions are essential to keep pace with the rapidly evolving CAR T cell therapy landscape.

KEY MARKET PLAYERS

A few of the notable companies dominating the North American CAR T cell therapy market profiled in this report are Mustang Bio, Inc., Celgene Corporation, Bluebird Bio, Inc., CARsgen Therapeutics, Ltd., Novartis International AG, Legend Biotech, Sorrento Therapeutics Inc., Kite Pharma, Inc., Immune Therapeutics, Bellicum Pharmaceuticals, Inc. and Pfizer, Inc.

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Anil Kumar P is research manager at Market Data Forecast and responsible for Healthcare Domain.

Author

Anil Kumar P (Research Manager - Healthcare)

Anil Kumar P is the lead author of this report and the manager of the team responsible for authoring healthcare reports at Market Data Forecast. He holds a Bachelor’s degree in Pharmacy (Hons.) from BITS Pilani, one of India’s premier institutions. Over the past seven years, Anil has gained extensive experience working with multiple market research companies, where he has collaborated with a diverse range of clients—from innovative startups to Fortune 500 companies—delivering data-driven insights and strategic advice that drive business growth.

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Frequently Asked Questions

What are the factors driving the growth of the North America CAR T cell therapy market?

The growing investments in research and development, growing patient population seeking personalized treatments, favorable reimbursement policies, and the approval of CAR T cell therapies by regulatory authorities primarily drive the North American market growth.

What are the key challenges faced by the North America CAR T cell therapy market?

High treatment costs, limited availability of skilled professionals, infrastructure limitations, and the occurrence of side effects associated with CAR T cell therapy primarily challenge the market growth in North America.

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