Laser Capture Microdissection Market

Global Laser Capture Microdissection Market Size (2023 to 2028)

The size of the global laser capture microdissection market is expected to grow at a CAGR of 14.12% from 2023 to 2028 and be worth USD 174.4 million in 2023 to USD 337.5 million in 2028.

Laser capture microdissection (LCM) is a non-contact, contamination-free method of isolating single cells or large sections of tissues from a wide range of samples under direct microscopic inspection. The original morphology of the dissected tissue sample can be preserved with this approach. This approach separates specific cells by dissecting undesirable cells and directly harvesting the cells of interest, resulting in pure enriched cells. The real morphology of the dissected cell or tissue sample is preserved due to this. Using a laser beam and direct microscopic viewing, laser capture microdissection (LCM) is a high-resolution way of isolating cells from their surrounding tissues. It collects pure enhanced cell populations from tissue, blood, and sperm samples using UV, infrared, and immunofluorescence laser beams. Amplifying these nucleic acids to produce sufficient materials for downstream high-throughput analysis, cells collected via LCM have been largely used for DNA and RNA analysis for any specific cell type within complex organs and tissues of plants (such as sequencing).

MARKET DRIVERS:

Increased healthcare spending and the technical advantages of LCM are majorly propelling the global laser capture microdissection market growth.

New technologies have allowed scientists to understand better activities occurring at the subcellular level. Laser capture microdissection (LCM) has been identified as a key approach for collecting homogeneous cells with pinpoint accuracy, making it an effective way for obtaining pure cell populations in molecular studies. One of the other key drivers driving the market is the growing use of molecular analysis in bioscience research laboratories, fueled by the developing healthcare industry. Furthermore, because LCM enables sensitive analytical procedures to examine cell populations in-vivo, such as Hodgkin's disease malignant cells and cancer in situ, its sales are increasing worldwide. This, together with the rising demand for LCM in forensic science and molecular biology labs to acquire interpretable DNA profiles, is propelling the market forward. Growing application areas for this technology in sectors such as forensic science, diagnostics, and molecular biology are boosting the laser-capture microdissection market across the world.

Increasing financing and expenditure on research and development efforts by the market participants is further anticipated to accelerate the growth rate of the global laser capture microdissection market.

The establishment of "genetic fingerprints" of specific pathological lesions, particularly malignant neoplasms, population growth, technological advancement, contamination-free technique, and improved healthcare infrastructure are other positive factors influencing the laser capture microdissection market. Furthermore, the formation of tailored treatments based on a tumor's molecular profile and developing markets provide lucrative opportunities for laser-capture microdissection market players. LCM systems with immunofluorescence laser diodes are also likely to be improved by several companies. Compared to other biotechnology markets, the global laser capture microdissection market has grown.

MARKET RESTRAINTS:

On the other hand, costly equipment and accessory manufacture and maintenance costs, a scarcity of personnel with advanced technical skills, and technological flaws in RNA degradation are major factors expected to limit the growth rate of the global laser capture microdissection market. Furthermore, the global laser capture microdissection market is further expected to be challenged by concerns with RNA degradation and the time-consuming sample preparation process over the forecast period.

REPORT COVERAGE:

This research report on the global laser capture microdissection market has been segmented and sub-segmented based on product, application, end-users & region.

Laser Capture Microdissection Market – By Product

• Consumables
• Reagents and Media
• Assay Kits
• Instruments
• Software and Services

The software & Services segment had the largest share of the global market in 2022. In this, China will continue to be one of the fastest expanding.

Laser Capture Microdissection Market – By Application:

• Research and Development
• Molecular Biology
• Cell Biology
• Forensic Science
• Diagnostics

Over the forecast period, the diagnostics segment is expected to grow at the highest CAGR. Microdissection of tissue sections and cytological preparations are now being employed more frequently to isolate homogeneous, morphologically identifiable cell groups, overcoming the challenge of tissue complexity. In addition, microdissection, combined with sensitive analytical techniques such as the polymerase chain reaction, allows for precise in-vivo examination of cell populations that are otherwise inaccessible for conventional molecular studies.

Laser Capture Microdissection Market – By End-User:

• Academic and Government Research Institutes
• Hospitals
• Pharmaceutical and Biotechnology Companies
• Contract Research Organizations (CROs)

The pharmaceutical and biotechnology companies segment is expected to register a robust due to rising investment in pharmaceutical research and the growing adoption of laser capture microdissection to conduct in vivo analysis of cells such as cancer cells to develop advanced therapeutics over the forecast period. Furthermore, the UV laser-capture microdissection system allows for exact sample collection. DNA and RNA extracted using this method can be employed in various downstream applications, including a polymerase chain reaction.

Laser Capture Microdissection Market – By Region:

• North America
• Europe
• Asia-Pacific
• Latin America
• Middle East and Africa

Geographically, the APAC region is expected to grow at the fastest CAGR during the forecast period in the global market. The market for laser-capture microdissection in the Asia Pacific is being driven by increasing expenditure on research and development efforts by firms in this market and raised awareness about technological improvement. China, Japan, and India contribute to the market's strong growth in the Asia Pacific.

North America dominates the global laser capture microdissection market, owing to an ample supply of trained workers. In addition, the United States has a robust healthcare infrastructure, which is complemented by substantial funding for medical research programs. This will continue to drive laser capture microdissection usage in North America.

KEY MARKET PARTICIPANTS:

Companies playing a promising role in the global laser capture microdissection market profiled in this report are Carl Zeiss AG, Molecular Machines & Industries, Ocimum Biosolutions LLC., DeNova Sciences Pte. Ltd., Danaher Corporation, Thermo Fisher Scientific, Inc., Indivumed GmbH, AvanSci Bio, L.L.C., Theranostics Health, Inc., 3DHISTECH Ltd., Promega Corporation, VitroVivo Biotech, and Precision MicroFab LLC.

RECENT HAPPENINGS IN THIS MARKET:

• Fludigm launched the AccuLift Laser Capture Microdissection System in 2020 to advance translational and clinical pathology research.