Hyaluronidase Market

Global Hyaluronidase Market Size (2024 to 2029)

The global market size for hyaluronidase is forecasted to grow at a CAGR of 9.04% from 2024 to 2029 and be worth USD 1578.2 million by 2029 from USD 1023.8 million in 2024.

Hyaluronidase is an injectable enzyme solution that aids in the natural decomposition of hyaluronic acid. Local anesthetics, chemotherapeutics, and contrast media have all been utilized as spreading agents with these enzymes. When a drug cannot be injected into a vein, it is mixed with other drugs and injected under the skin to improve absorption by the body. It also helps radioactive chemicals absorb better during subcutaneous urography. Hyaluronidase is used in combination with fluid injections to treat dehydration. It's also used to aid the body's absorption of other drugs injected into the body. Hyaluronidase can also help contrast dyes in the body show up more clearly on some scans or X-rays. Hyaluronidases are a type of enzyme that can be found in various venoms and toxins.

MARKET DRIVERS

The presence of multiple clinical studies to establish the efficacy of the products, rising awareness of physical appearance changes, and increasing penetration across various application sectors are fuelling the expansion of the global hyaluronidase market.

The growing awareness of the importance of changing one's physical appearance has resulted in a surge in demand for cosmetic and aesthetic procedures. The rising prevalence of skin problems and the easy availability of advanced aesthetic treatments drive the market for hyaluronidase in cosmetic dermatology. In addition, using enzyme-based substrates for noninvasive tumor imaging in cancer metastasis and multiple applications in cancer therapy, aesthetic treatments, and ophthalmic therapeutic solutions are essential to market drivers. Cancer has become the second biggest cause of mortality worldwide, after cardiovascular diseases. This phenomenon is caused by environmental variables such as shifting dietary trends, urbanization, and a longer post-reproductive lifespan. As a result, the rising occurrence of cancer boosts market growth.

Furthermore, the growing senior population, favorable payment policies, and growing number of patients choosing nonsurgical procedures further accelerate market growth. In addition, rapid technological advancements in healthcare are increasing R&D, and hyaluronidase-based medicines are readily available in hospitals and medical stores, all of which are likely to create new opportunities that will impact the growth of the hyaluronidase market in the forecast period. The practitioner/beautician must be well-versed in the proper dosage of hyaluronidase and any potential problems and necessary treatments. Rising innovations aimed at lowering the negative effects of hyaluronidase administration are projected to provide profitable opportunities for key companies in the market.

MARKET RESTRAINTS

The various side effects of the product on the human body and the high expenditure involved in research and development are expected to act as significant restraints on the growth of the global hyaluronidase market. Skin rashes, irregular heartbeats, dizziness, and unusual weakness are expected to hamper the market in the near future. A lack of awareness may challenge the market's growth during the forecast period.

REPORT COVERAGE

SEGMENTAL ANALYSIS

Global Hyaluronidase Market Analysis By Type

The animal-derived hyaluronidase segment had the most significant share of the market in 2023. Most approved and commercialized brands are now sourced from animal sources; thus, it is likely to keep their dominance throughout the forecast period. Furthermore, recombinant human hyaluronidase has been shown in several investigations to improve the quality and safety of local anesthetic blocks. In addition, the absorption of other injectable fluids in the body is likely to be aided by animal-derived Hyaluronidase, making the treatment process less dangerous. As a result of these considerations, animal-derived hyaluronidase is predicted to grow in popularity over the forecast period.

Global Hyaluronidase Market Analysis By Application

The dermatology segment is expected to dominate the worldwide hyaluronidase market during the forecast period. The hyaluronidase enzyme aids in the diffusion and absorption of injected fluids in the tissues. It also improves the effectiveness of local anesthetics and reduces the danger of necrosis.

Global Hyaluronidase Market Analysis By End-user

To manage hyaluronic acid injection problems efficiently, clinicians must be well-informed of their symptoms. In addition, it is critical to have good action plans for emergencies in which the needed agents are readily available at the operation or treatment site.

REGIONAL ANALYSIS

The hyaluronidase market in North America was the largest worldwide in 2023. Because of key firms manufacturing these drugs, the high acceptance of innovative treatment alternatives, and the large number of dermatological clinics prescribing such therapies, North America is likely to hold a significant share in the global hyaluronidase market during the forecast period. Furthermore, rising healthcare spending and well-established healthcare infrastructure contribute to the overall regional market's growth. The United States plays a crucial role in North America's geographic contribution to the worldwide hyaluronidase market, owing to the increasing adoption of facial aesthetic procedures and the desire for minimally invasive cosmetic procedures.

Due to medical tourism in dermatology and chemotherapy in many nations, Asia Pacific will witness the most significant rise. Many worldwide corporations have begun to invest in the Asia-Pacific region. The Asian market has risen quickly due to many providers and advancements in technology. South Korea is second only to China in terms of income generation. Alteogen copyrighted its protein engineering technology after developing the world's second human recombinant hyaluronidase (recombinant) protein.

KEY PLAYERS IN THE GLOBAL HYALURONIDASE MARKET

Amphastar Pharmaceuticals Inc., Halozyme Inc., Bausch & Lomb Incorporated, The Cooper Companies Inc., Sun Pharmaceutical Industries Ltd., STEMCELL Technologies Inc., Shreya Life Sciences Pvt. Ltd. and Calzyme are some of the noteworthy companies operating in the global hyaluronidase market profiled in this report.

RECENT HAPPENINGS IN THIS MARKET

• Herceptin Hylecta for Subcutaneous Injection in Certain HER2-Positive Breast Cancers Receives FDA Approval in 2019.

DETAILED SEGMENTATION OF THE GLOBAL HYALURONIDASE MARKET INCLUDED IN THIS REPORT

This research report on the global hyaluronidase market has been segmented and sub-segmented based on type, application, end-user, and region.

By Type

• Animal-derived Hyaluronidase
• Synthetic Hyaluronidase

By Application

• Dermatology
• Chemotherapy
• Ophthalmology
• Plastic Surgery

By End-User

• Hospitals
• Clinics
• Research Centers

By Region

• North America
• Europe
• Asia-Pacific
• Latin America
• Middle East and Africa