Gene Expression Analysis Market

Gene Expression Analysis Market Size (2024 to 2029)

The global gene expression analysis market size was valued at USD 6.50 Billion in 2024. It is further projected to be growing at a CAGR of 9.5% and be worth USD 10.22 Billion by 2029.

MARKET DRIVERS

The growing number of research activities on DNA studies, the rising cancer patient population worldwide and increasing applications of gene expression analysis in diagnostics and treatment propel the market growth. Decreasing costs of gene sequencing and various technological advances, such as biochips that help in studying DNA even better, are expected to propel the market. The growing incidence of chronic diseases worldwide and the increasing research activities to develop new drugs are prominent factors driving the market's growth rate. The growing prevalence of drug discovery and pharmacogenomics in pharmaceutical companies greatly supports the gene expression analysis market. Various applications of genomics and growing expenditure on healthcare services, especially in rural areas, are further accelerating the growth rate of the gene expression analysis market.

Moreover, growth opportunities for the market lie in the increasing investments by the governments in the research and development centers in biotechnology to evaluate new products at a low cost. Creating awareness of the applications of genomics and its advantages through campaigns and digital advertisements also surges the growth rate of the gene expression analysis market. In addition, the introduction of innovative procedures with the help of the latest technologies, the growing scale of pharmaceutical companies, and the increasing demand for targeted therapies are bolstering the demand for the gene expression analysis market. Rising capital income in developed and developing countries is another attribute of gearing market growth. Reducing the cost of sequencing techniques and growing demand to evaluate quality treatment procedures are fuelling market growth.

MARKET RESTRAINTS

However, strict rules for approving the latest equipment by government organizations are quietly hampering the growth of the gene expression analysis market. Also, this equipment requires massive amounts for installation and maintenance in the laboratories, which is a challenging factor for the market players. Moreover, it is ideal to have a suitable control for each cDNA found on the array. Currently, available filter arrays do not offer these controls. Additionally, table mistakes could result from contamination in the screening procedure's clones. The need for more skilled professionals to analyze the outcomes slightly limits the market's growth rate. In addition, the lack of complete knowledge of the procedure in undeveloped countries impedes the market's growth. Therefore, the absence of skilled professionals, lack of awareness, and the high price of the instruments used for the analysis are some of the major factors restraining the gene expression analysis market.

Impact of COVID-19 on the global gene expression analysis market

The COVID-19 pandemic caused a mixed impact on the growth of the gene expression analysis market. The gene expression analysis technologies and services have been increasingly used in the development of vaccines and therapeutics and this has boosted the market growth. The need for rapid and accurate diagnostic tests for COVID-19 has further accelerated the demand for gene expression analysis and favored the market growth during the COVID-19 pandemic. On the other hand, situations such as disruptions in global supply chains for supply chain for gene expression analysis technologies and services, closure of research laboratories and reduced funding for research caused by the COVID-19 pandemic shared an unfavorable impact on the gene expression analysis market. Likewise, the market has had a mixed impact from the COVID-19 pandemic. However, the demand for gene expression analysis is anticipated to accelerate in the coming years and the market will register notable growth during the forecast period.

REPORT COVERAGE

SEGMENTAL ANALYSIS

Gene Expression Analysis Market Analysis By Technology

Based on technology, the DNA microarray and NGS segments are predicted to occupy the major share of the global market during the forecast period as these are the most used technology categories. These techniques contribute a significant share to the expression analysis market. This can be attributed to the micro-level analysis of gene expression. DNA microarray uses chip-based technology that reveals gene expression and helps trace the sequence of the genes. Next-generation sequencing, also known as NGS, is a type of DNA sequencing technology that uses parallel sequencing of multiple small DNA fragments, providing opportunities for gene expression profiling in various contexts. An excellent complement to the present methodology to study specific genes' response to stimuli and discover potentially novel genes or transcripts, which has dramatically increased the speed at a decreased cost for individual genome sequencing.

Gene Expression Analysis Market Analysis By Consumables

Based on consumables, the DNA chips segment is expected to dominate the market during the forecast period. This is because DNA chips are mostly preferred for analyzing the sequence of genes easily using DNA chips. A DNA chip or biochip is a microscopic DNA dots collection affixed to a solid surface, used by scientists to genotype multiple regions of a genome. To detect gene expression, also known as the transcriptome or the collection of messenger RNA (mRNA) transcripts expressed by a gene cluster, DNA molecules linked to each slide serve as probes.

The reagents segment is also anticipated to foreseen to hold a substantial market share globally during the forecast period. By cataloging the variety of mutations, these mutation detection techniques can be used to diagnose genetic disorders in both prenatal and neonatal patients and to understand the function of the afflicted protein. Here is a review of two such mutation detection methods. Both procedures involve chemically altering mismatched nucleotides, either with carbodiimide or hydroxylamine and osmium tetroxide. The techniques are known as chemical mismatch cleavage (CCM) and carbodiimide (CDI) approaches.

Gene Expression Analysis Market Analysis By Services

Based on Services, the gene expression profiling segment holds the largest market share due to the rising number of gene expression analysis tests. Gene expression profiling is used to measure mRNA levels, which show the pattern of genes expressed by a cell at the transcription level. This sometimes entails comparing the relative amounts of mRNA produced under two or more different experimental circumstances before determining which led to the expression of particular genes.

The bioinformatics segment is estimated to register the fastest growth rate during the forecast period. Bioinformatics is the latest technology that is growing at a faster pace. Bioinformatics is an interdisciplinary field that involves mathematics, computer science, physics, and biology. It is the application of computational and analytical tools for interpreting biological data used by Scientists and clinicians to organize and index biological information to improve medical care and understand health and disease. The growth can be attributed to technology and devices that sequence genes using information technology and artificial intelligence.

Gene Expression Analysis Market Analysis By Application

Based on the application, the research segment is anticipated to lead the gene expression analysis market during the forecast period. Research is the primary market for gene expression analysis, for analyzing disease-causing organisms, and it is used in analyzing for making drugs to treat such disorders. Of all these segments, research holds a significant share. But Gene expression analysis is also being used in diagnostics at a large scale; this can be attributed to the increased rate of gene therapies. Cancer is a hereditary disease where genetic abnormalities lead to genes that act abnormally and seem to change expression. Phenotypes and biological processes are controlled by proteins, which are the result of gene expression. As a result, gene expression levels can be detected in a clinical situation to predict cancer diagnosis, prognosis, and treatment.

REGIONAL ANALYSIS

Geographically, the North American gene expression analysis market had the leading share of the global market in 2023 and is estimated to record the highest share in the global gene expression analysis market during the forecast period The growth of the North American market is primarily attributed to the active participation of several key players like Thermo Fisher Scientific. The presence of well-established research infrastructure and academic institutions and the availability of advanced genomic technologies and high adoption rates further contribute to the growth rate of the North American market. The U.S. accounted for the largest share of the North American market in 2023 and the trend is expected to continue during the forecast period due to the presence of several key market leaders such as Thermo Fisher Scientific, Illumina, and Qiagen in the United States.

The European gene expression analysis market is expected to be the second-largest regional market, accounting for an impressive global gene expression analysis market share during the forecast period. Factors such as the rising interest of dominant players in the European region and the increasing adoption of advanced technologies contribute to market growth in the European region. The favorable regulatory environment for genomics research, rising emphasis on personalized medicine and precision oncology and growing investments in genomics research and infrastructure further boost the growth rate of the European market.

However, the Asia Pacific gene expression analysis market is the fastest-growing regional market for gene expression analysis worldwide. It is expected to account for a substantial share of the global market during the forecast period. The growing number of investments from the governments of the APAC region in genomics research and precision medicine, the increasing number of collaborations and partnerships between academia and industry, the rising healthcare infrastructure, and the adoption of advanced technologies majorly propel the APAC market growth. China and India are estimated to hold the major share of the APAC market in the coming years owing to the growing investments by governmental and private organizations to improve healthcare infrastructure.

The Latin American gene expression analysis market is predicted to grow steadily during the forecast period. The growing number of research collaborations and partnerships, rising emphasis on precision medicine and genomic research in healthcare and growing prevalence of chronic diseases drive the gene expression analysis market in the Latin American region.

The Middle East & Africa Gene Expression Analysis Market is projected to grow sluggishly during the forecast period. UAE is leading with the highest shares of the market. On the other hand, countries like Qatar are to exhibit significant developments according to their respective genomics and personalized medicine fields.

KEY MARKET PARTICIPANTS

The report's promising companies leading the global gene expression analysis market are Thermo Fisher Scientific, Inc, G.E. Healthcare, QIAGEN N.V., Life Technologies, Agilent Technologies, Roche, PerkinElmer, Affymetrix, Illumina, Inc, Bio-Rad Laboratories, Oxford Gene Technology, Luminex Corporation.

RECENT MARKET HAPPENINGS

• In November 2022, an innovative biotechnology company, Silence Therapeutics plc, presented data from Phase 1 APOLLO single-dose analysis, showing maintenance of median reductions more significant than 80% in people with SLN360 single dose.
• In November 2022, Singleton Biotechnologies, a pioneer in developing single-cell sequencing analysis solutions, launched the ProMoSCOPE kit, helping make advanced high-throughput single-cell multimodal analysis more accessible.
• In October 2022, Oxford Nanopore Technologies plc collaborated with 10x Genomics to help users with the ability to encompass users to features like yielding rich and cost-effective single-cell and spatial sequencing data.
• In August 2018, the NovoFocus NSCLC CDx test received CFDA approval and was launched by the Tianjin Novogene Bioinformatics Technology subsidiary of Novogene Co. This is a diagnostic test that analyzes tumor samples based on next-generation sequencing.
• In January 2017, the acquisition of Biorad and RainDance Technologies was announced. The acquisition between these companies will focus on the development of droplet-based technologies, digital PCR (dPCR).

DETAILED SEGMENTATION OF THE GLOBAL GENE EXPRESSION ANALYSIS INCLUDED IN THIS REPORT

This market research report on the global gene expression analysis market has been segmented and sub-segmented into the following categories.

By Technology

• DNA Microarray
• PCR
• NGS
• SAGE
• Northern Blotting

By Consumables

• DNA Chips
• Reagents

By Services

• Gene Expression Profiling
• Bioinformatics

By Application

• Research
• Drug Discovery
• Diagnostics

By Region

• North America
• Europe
• Asia-Pacific
• Latin America
• Middle East and Africa