Demineralized Bone Matrix Market

Global Demineralized Bone Matrix Market Size (2024 to 2029)

The global demineralized bone matrix market was valued at USD 719.5 million in 2023. The global market is estimated to be worth USD 970.8 million by 2029 from USD 756.3 Million in 2024, growing at a CAGR of 5.12% from 2024 to 2029.

MARKET DRIVERS

The growing aging population who are susceptible to bone degeneration and fractures is majorly driving the demineralized bone matrix market growth.

The number of people aging is increasing rapidly worldwide. As per the estimates of the World Health Organization (WHO), the number of people with 60 years and above worldwide is expected to hit 2.1 billion by 2050. The possibility of experiencing bone degeneration and fractures among people grows with age and people who are aged will have a higher risk of these conditions. The growing aging population suffering from these conditions is likely to generate more demand for demineralized bone matrix and drive market growth.

The rising prevalence of bone-related disorders and injuries and the growing number of dental surgeries, such as dental implant procedures and bone grafting procedures for various tooth conditions, majorly propel the growth of the demineralized bone matrix market.

The rising adoption and demand for minimally invasive surgeries contribute to the market growth. Minimally invasive surgical procedures have several benefits less pain, fewer complications, and faster recovery. Demineralized bone matrix is used to perform minimally invasive procedures. The growing R&D activities in the demineralized bone matrix field, technological advancements, rising healthcare spending and the growing patient population suffering from dental and orthopedic disorders drive the market growth.

The growing number of advancements in bone grafting techniques and materials, rising awareness about the benefits of DBM in bone regeneration, favorable reimbursement policies for DBM procedures, technological advancements in DBM processing and manufacturing and growing investments in research and development of innovative DBM products support the market growth. The expansion of healthcare infrastructure in emerging economies, rapid adoption of DBM in sports medicine and orthobiologics, increasing number of collaborations and partnerships between key market players, growing demand for regenerative medicine and tissue engineering and the availability of a wide range of DBM products catering to specific clinical needs boost the growth rate of the DBM market. Factors such as the rising preference for natural and biocompatible bone graft substitutes, growing healthcare expenditure, increasing disposable income, supportive government initiatives and funding for bone-related research, rising awareness about the advantages of DBM over traditional bone grafting methods and growing focus on personalized medicine and patient-centric approaches in healthcare further favor the growth rate of the demineralized bone matrix market.

MARKET RESTRAINTS

Limited availability of high-quality donor bone for DBM production, stringent regulations and complex approval processes for DBM products and high costs associated with DBM procedures and products majorly hamper the growth of the demineralized bone matrix market. Risk of disease transmission or infection from allograft DBM materials, limited reimbursement coverage for DBM procedures by insurance providers and competition from alternative bone graft substitutes and synthetic materials inhibit the market’s growth rate. Challenges in maintaining DBM product consistency and quality control and poor awareness and understanding among healthcare professionals about DBM benefits and applications impede the market growth.

REPORT COVERAGE

SEGMENTAL ANALYSIS

Global Demineralized Bone Matrix Market Analysis By Product Type

The putty segment dominates the demineralized bone matrix market during the forecast period owing to factors such as the growing prevalence of orthopedic diseases, the rising number of dental conditions and the increasing adoption of putty products. The versatility of putty in filling and contouring bone voids or gaps, enhanced stability and structural support of putty for bone healing and ease of shaping and molding to fit various anatomical sites contribute to the segmental growth. Effective delivery and retention of growth factors or osteoinductive agents and suitable for both small and large bone defect reconstructions further boost the growth rate of the putty segment.

The gel segment is also anticipated to grow at a promising CAGR during the forecast period due to the increasing number of trauma surgeries and the biocompatible nature of the gel products. Ease of application and handling, enhanced adaptability and conformability to irregular bone defects and improved surgical precision and control during implantation drive the growth of the gel segment. Reduced risk of graft migration or displacement and favorable outcomes in achieving bone regeneration and fusion further propel the growth of the gel segment.

Global Demineralized Bone Matrix Market Analysis By Application

Based on application, the spinal fusion segment is predicted to account for the major share of the global demineralized bone matrix market during the forecast period owing to factors such as the growing number of spine surgeries and the rising prevalence of spinal disorders. The growing aging population with spinal issues and chronic back pain, favorable clinical outcomes in achieving spinal fusion and stability, technological advancements in spinal implants and surgical techniques and growing demand for minimally invasive spinal fusion procedures primarily drive the growth of the spinal fusion segment.

The dental segment is estimated to grow at a notable CAGR during the forecast period owing to the rising usage of demineralized bone matrix products for dental surgeries. The growing prevalence of dental disorders and tooth loss, rising demand for dental implant procedures and favorable outcomes in promoting bone regeneration for dental implants drive the growth of the dental segment. The growing adoption of DBM in periodontal and oral surgery procedures and increasing advancements in dental implant technologies and materials further boost the growth rate of the dental segment.

REGIONAL ANALYSIS

North America dominated the demineralized bone matrix market in 2022 and the domination of the North American region in the worldwide market is most likely to continue throughout the forecast period. Factors such as the presence of advanced healthcare infrastructure and technological capabilities, the growing prevalence of bone-related disorders and orthopedic surgeries and favorable reimbursement policies for bone grafting procedures primarily drive the market growth in the North American region. The growing investments in research and development of regenerative medicine, strong presence of key market players and continuous product advancements further propel the North American market growth.

Europe had the second-largest share of the global market in 2022 and is anticipated to account for a substantial share of the worldwide market during the forecast period. Factors such as the growing aging population prone to bone degeneration and fractures, rapid adoption of advanced orthopedic procedures and techniques and supportive government initiatives for healthcare infrastructure development primarily drive the European market growth. The growing awareness about the benefits of DBM in bone regeneration and an increasing number of collaborations between research institutes and industry for innovation in bone grafting boost the growth rate of the European market.

APAC is the most lucrative regional market for demineralized bone matrix and is predicted to witness the highest CAGR during the forecast period among all the regions. The presence of a large population, increasing healthcare expenditure, growing patient population of orthopedic disorders and trauma injuries and the expansion of healthcare infrastructure and accessibility in emerging economies majorly drive the APAC market growth. The rapid adoption of advanced surgical techniques and implants and growing investments in regenerative medicine and tissue engineering further accelerate the growth rate of the APAC market.

KEY PLAYERS IN THE GLOBAL DEMINERALIZED BONE MATRIX MARKET

Medtronic, Xtant Medical, Zimmer Biomet, SeaSpine, Johnson and Johnson, Arthrex, Stryker, Hans Biomed, Straumann, Wright Medical Group and RTI Surgical are some of the major companies in the global demineralized bone matrix market.

RECENT HAPPENINGS IN THE MARKET

• In July 2021, RTI Surgical, a leading surgical implant company that provides blue-chip OEM customers with a portfolio of tissue-based, synthetic, and metal implants, announced that it has signed a long-term strategic agreement with leading global medical device OEM Exactech, related to the development and supply of biologic bone substitutes. RTI Surgical acquired the demineralized bone matrix offered by Exactech under the brand name Optecure. This bone graft extender matrix has been given 510(k) clearance and is intended for use in the extremities, spine, and pelvis as a bone graft extender.
• In February 2021, Kolosis BIO, LLC made an announcement today along with MTF Biologics (MTF) on the launch of Kore Fibre onto the market. Kore Fibre is a demineralized cortical fibre allograft that has been produced especially for Kolosis.

DETAILED SEGMENTATION OF THE GLOBAL DEMINERALIZED BONE MATRIX MARKET INCLUDED IN THIS REPORT

This research report on the global demineralized bone matrix market has been segmented and sub-segmented based on the product type, application & region.

By Product Type

• Gel
• Putty
• Others

By Application

• Dental
• Spinal Fusion
• Joint Reconstruction
• Others

By Region

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East and Africa